The Arc Institute has introduced Evo, an advanced AI model trained on 2.7 million microbial genomes, capable of interpreting and generating genetic sequences with unprecedented accuracy. Dubbed the 'ChatGPT for DNA,' Evo can predict the effects of gene mutations and design synthetic CRISPR and transposon systems. This model maintains single nucleotide resolution while interpreting large genomic sequences, potentially revolutionizing research in synthetic biology and bioinformatics. By accelerating the design of new proteins for drug development and enhancing the understanding of genetic mutations, Evo is positioned to significantly impact various applications in genomics and biotechnology.