The emergence of large language models (LLMs) is transforming biomedical research, although their commercial use remains limited. BioChatter has been introduced as an open-source framework designed specifically for developing LLMs tailored to biomedical applications. This initiative is part of a broader trend, with various platforms and organizations, including the Chan Zuckerberg Initiative, emphasizing the potential of LLMs to enhance research capabilities. Recent advancements have led to the creation of initial cell models aimed at helping researchers understand the cellular basis of health and disease. The ongoing development of these technologies is expected to yield further innovations in the field.