OpenFold, an open-source tool, is transforming protein modeling by leveraging artificial intelligence and supercomputing capabilities. This innovation holds significant potential for advancing drug discovery and understanding complex biological processes, including neurodegenerative diseases. Experts in the field are discussing the implications of AI in biological research, emphasizing its role in accelerating experiments and creating new biological structures. Additionally, recent perspectives highlight how AI applications are revolutionizing protein engineering and enabling the development of a 'virtual cell' for enhanced modeling of biological systems. The integration of AI into structural biology is being explored through various platforms, showcasing its impact on scientific research and drug development.