Terry Ragon, the founder of the software company InterSystems, has become a billionaire and is now channeling his wealth into medical research. He and his wife Susan have donated $400 million to develop a vaccine for HIV. Ragon believes that by bringing together top doctors, scientists, and engineers, he can succeed in curing one of the world’s most challenging viruses, where major governments have previously failed. Founded in 1978, InterSystems has been a significant player in health data management, and Ragon is leveraging this expertise in his philanthropic efforts.