Holden News

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#144 – Athena Aktipis on why cancer is actually one of the fundamental phenomena in our universe

#145 – Christopher Brown on why slavery abolition wasn't inevitable

#146 – Robert Long on why large language models like GPT (probably) aren't conscious

#147 – Spencer Greenberg on stopping valueless papers from getting into top journals

#148 – Johannes Ackva on unfashionable climate interventions that work, and fashionable ones that don't

#151 – Ajeya Cotra on accidentally teaching AI models to deceive us

#149 – Tim LeBon on how altruistic perfectionism is self-defeating

#150 – Tom Davidson on how quickly AI could transform the world

#152 – Joe Carlsmith on navigating serious philosophical confusion

#153 – Elie Hassenfeld on two big picture critiques of GiveWell's approach, and six lessons from their recent work

#154 – Rohin Shah on DeepMind and trying to fairly hear out both AI doomers and doubters

#155 – Lennart Heim on the compute governance era and what has to come after

#156 – Markus Anderljung on how to regulate cutting-edge AI models

#157 – Ezra Klein on existential risk from AI and what DC could do about it

#158 – Holden Karnofsky on how AIs might take over even if they're no smarter than humans, and his 4-part playbook for AI risk

#159 – Jan Leike on OpenAI's massive push to make superintelligence safe in 4 years or less

#160 – Hannah Ritchie on why it makes sense to be optimistic about the environment

#161 – Michael Webb on whether AI will soon cause job loss, lower incomes, and higher inequality — or the opposite

#162 – Mustafa Suleyman on getting Washington and Silicon Valley to tame AI

#163 – Toby Ord on the perils of maximising the good that you do

#166 – Tantum Collins on what he's learned as an AI policy insider at the White House, DeepMind and elsewhere

#167 – Seren Kell on the research gaps holding back alternative proteins from mass adoption

#168 – Ian Morris on whether deep history says we're heading for an intelligence explosion

#164 – Kevin Esvelt on cults that want to kill everyone, stealth vs wildfire pandemics, and how he felt inventing gene drives

#165 – Anders Sandberg on war in space, whether civilisations age, and the best things possible in our universe

#169 – Paul Niehaus on whether cash transfers cause economic growth, and keeping theft to acceptable levels

#170 – Santosh Harish on how air pollution is responsible for ~12% of global deaths — and how to get that number down

#171 – Alison Young on how top labs have jeopardised public health with repeated biosafety failures

#172 – Bryan Caplan on why you should stop reading the news

#173 – Jeff Sebo on digital minds, and how to avoid sleepwalking into a major moral catastrophe

#174 – Nita Farahany on the neurotechnology already being used to convict criminals and manipulate workers

#175 – Lucia Coulter on preventing lead poisoning for $1.66 per child

Elon Musk

Sarah Paine

Dean Ball

Dwarkesh Patel (see note)

Demis Hassabis

Dylan Patel (as guest)

Dean Spears

Yann LeCun

Tyler Cowen

Tamay Besiroglu

Satya Nadella

Holden Karnofsky

Alec Radford

Gary Marcus

Amanda Askell

François Chollet

Joscha Bach

Sundar Pichai

Jack Clark

Jensen Huang

Michael Dell

Mira Murati

Joe Carlsmith

Ian Morris

Sam Altman

Bill Gates

Nick Bostrom

roon

Paul J Werbos

Zvi Mowshowitz

Matt Levine

George Hotz

Helen Toner

Ajeya Cotra

Noam Brown

Hans Moravec

Mustafa Suleyman

Doris Taylor

Jeff Bezos

Michael Levin

Eliezer Yudkowsky

Carl Shulman

Ilya Sutskever

David Reich

Janus @repligate

Tanner Greer

Mark Zuckerberg

Dan Hendrycks

Liang Wenfeng (CEO of DeepSeek)

Nate Soares

Joe Henrich

Andrej Karpathy

Scott Alexander

Barack Obama

Robert Caro

Xiao Hong (CEO of Manus AI)

Kamala Harris

Donald Trump

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