A recent study has found that COVID-19 vaccination reduces the risk of severe kidney damage in patients hospitalized with the virus. Among patients hospitalized with COVID-19 and acute kidney injury, those who were vaccinated showed better outcomes compared to unvaccinated patients. Vaccinated individuals were less likely to require dialysis or continuous renal replacement therapy (CRRT) after hospital discharge. The study also reported that unvaccinated patients had 2.56 times higher odds of needing CRRT post-discharge, 5.54 times greater risk of dying during hospitalization, and 4.78 times higher risk of death during long-term follow-up compared to vaccinated patients. The study involved 972 participants who developed acute kidney injury during their COVID-19 hospitalization. These findings suggest that vaccination not only protects against COVID-19 infection but also mitigates severe complications such as kidney failure. However, it was noted that in 2020, 46% of hospitalized patients with COVID-19 and acute kidney injury were vaccinated, indicating a substantial proportion of vaccinated individuals still experienced kidney injury. Overall, the data underscores the protective effect of COVID-19 vaccines against severe renal outcomes in hospitalized patients.