Fourth-tier Grimsby Town knocked six-time winners Manchester United out of the Carabao Cup on Wednesday, prevailing 12-11 in a marathon penalty shoot-out after the tie finished 2-2 in regulation at a rain-soaked Blundell Park. Charles Vernam put the League Two side ahead in the 22nd minute and former United academy defender Tyrell Warren doubled the advantage after an error by returning goalkeeper Andre Onana. United’s £200 million strike force avoided outright defeat when substitute Bryan Mbeumo pulled one back on 75 minutes and Harry Maguire forced extra time with an 89th-minute header. But Mbeumo struck the crossbar with his second attempt in the shoot-out, allowing Grimsby — cheered on by a capacity 9,000 crowd — to record a 12-11 victory and spark a pitch invasion hailed as one of the greatest nights in the club’s 146-year history. The result marks Manchester United’s first loss to a fourth-tier opponent and intensifies scrutiny on head coach Ruben Amorim, whose side has managed just one point from two Premier League matches. “Everything went wrong — I can only apologise to our fans,” the Portuguese manager said, acknowledging that the club’s hopes of domestic silverware now rest largely on the FA Cup.