Manchester United host Arsenal at Old Trafford on Sunday in the first match of the 2025-26 English Premier League season, a high-profile curtain-raiser that pits a rebuilt United side against an Arsenal team seeking to convert successive runners-up finishes into a first league title since 2004. United manager Ruben Amorim, appointed after last season’s 15th-place finish, has overhauled his squad, adding forward Benjamin Sesko from RB Leipzig, winger Bryan Mbeumo from Brentford and striker Matheus Cunha from Wolves. Amorim is expected to field several of the newcomers as he looks to arrest the club’s worst domestic run in the modern era. Arsenal arrive with equal optimism after strengthening with Sweden striker Viktor Gyokeres and Spanish midfielder Martín Zubimendi. Manager Mikel Arteta said the additions give his side “a different level of threat” and greater depth for a demanding opening run that includes trips to Leeds, Liverpool, Manchester City and Newcastle. Recent history between the rivals is finely balanced: Arsenal are unbeaten in the last five meetings in all competitions, yet United have lost only twice in their previous 18 league encounters with the Gunners at Old Trafford. Sunday’s match, which kicks off at 11:30 a.m. ET, will provide an early gauge of whether Amorim’s overhaul can restore United to contention and whether Arteta’s tweaked squad can finally clear the last hurdle in the title race.