On July 2, 2022, at UFC 276, Alex Pereira delivered a first-round knockout to Sean Strickland with a powerful left hook, marking a defining moment in Pereira's UFC career. This victory demonstrated Pereira's ability to compete at the highest level of the division and has since been remembered as a significant highlight. The fight not only showcased Pereira's striking prowess but also led to an unexpected friendship between the two fighters. Pereira's performance continues to be celebrated as a key moment that elevated his status within the mixed martial arts community.