A multinational study involving approximately 2,390 participants across 18 countries and 38 centers has found that Covid-19 infection accelerates vascular aging, particularly in women. The research, published in the European Heart Journal, indicates an average increase in pulse wave velocity (PWV)—a marker of blood vessel stiffness—of 0.55 meters/second in women with mild Covid, 0.60 in hospitalized women, and 1.09 in women treated in intensive care units. An increase of 0.5 meters/second in PWV is considered clinically relevant. This vascular aging effect was observed even in non-hospitalized and mild to moderate Covid cases. The study also noted that vaccination appears to offer protective benefits against this accelerated vascular aging in female participants. Additionally, persistent symptoms in Covid-positive women were associated with higher PWV values (7.52 m/s versus 7.13 m/s). The findings suggest a sex-specific impact of Covid-19 on arterial aging, with potential implications for increased cardiovascular risk. Separate research has indicated that infections like Covid-19 and influenza may reactivate dormant cancer cells, raising concerns about cancer recurrence and metastasis, and highlighting the potential role of immune surveillance strategies such as cancer vaccines. Furthermore, scientists are reconsidering the long-term immune effects of SARS-CoV-2, including the concepts of immune debt and immune reset.