India has seen a substantial increase in organ transplants, rising from fewer than 5,000 in 2013 to over 18,000 in 2023, driven by advances in surgical techniques, improved organ preservation, better donor-recipient matching, and supportive policies. In 2024, India achieved a record number of organ transplants, although thousands of patients remain on waiting lists. Efforts to enhance transplant success include the implementation of coordinated, traffic-free routes that expedite the delivery of donor organs to recipients. On World Organ Donation Day 2025, the theme 'Answering the Call' highlights the critical role of medical, legal, and logistical teams in facilitating life-saving transplants. Brain death, legally recognized in India as death, allows for organ viability when the heart is still beating, underscoring the urgency and safeguards involved in the donation process. Meanwhile, India's MedTech regulatory framework has evolved from colonial-era drug regulations to comprehensive coverage under the Medical Device Rules (MDR) of 2017 and 2020. Experts emphasize that balancing price control with innovation is essential to unlocking a $50 billion market potential in the medical technology sector. Additionally, calls have been made for increased public participation in organ donation to address the ongoing demand and save more lives.