The U.S. Department of Justice (DOJ) has announced comprehensive updates to its corporate and white-collar enforcement policies, emphasizing a renewed focus on health care fraud and the most egregious crimes. The DOJ's Criminal Division unveiled a new enforcement plan that introduces clearer guidelines for corporate self-disclosure, stronger incentives for companies to report criminal conduct voluntarily, and an updated whistleblower awards pilot program. These changes aim to balance enforcement rigor with fairness and efficiency, potentially reshaping compliance expectations for corporate America. Additionally, the DOJ is intensifying antitrust enforcement, with plans to demand that Alphabet Inc.'s Google break up its online advertising business, reflecting a broader crackdown on monopolization under the current administration. The updated policies also signal a shift toward more declinations and fewer monitors in corporate enforcement, while the Foreign Corrupt Practices Act (FCPA) enforcement remains uncertain. The DOJ's revised approach presents ongoing risks for both U.S. and non-U.S. companies, underscoring the importance of compliance and proactive self-reporting in the evolving regulatory landscape.