State attorneys general across the United States have intensified their antitrust enforcement efforts, introducing new laws and exploring broader areas of focus. This surge in activity coincides with the early stages of the second Trump administration, which has emphasized a robust antitrust agenda within its first 100 days. Key federal agencies, including the Federal Trade Commission (FTC) and the Department of Justice (DOJ), continue vigorous enforcement despite previous deregulatory trends. High-profile cases against major technology companies such as Meta and Alphabet (Google) have persisted through political transitions from the Trump to Biden administrations and back, reflecting bipartisan interest in addressing Big Tech's market power. Meanwhile, the U.S. Patent and Trademark Office (USPTO) is accelerating patent issuance timelines and adjusting the role of its Delegated Rehearing Panel under the new administration. Legal experts highlight that enforcement strategies are evolving, with merger priorities and preparation for future antitrust waves being central themes. The ongoing Google antitrust trial remains a focal point as federal judges deliberate on potential breakup measures.