The Trump administration has initiated a comprehensive review of Harvard University's federally funded research programs, accusing the university of failing to comply with its legal obligations under the Bayh-Dole Act. Commerce Secretary Howard Lutnick sent a letter to Harvard President Alan Garber on August 8, warning that the federal government could assume ownership of or grant licenses for Harvard's patents, which are valued at hundreds of millions of dollars. This move represents an escalation in ongoing negotiations between the administration and Harvard, focusing on the university's management of its lucrative patent portfolio derived from federally funded research. The administration's action includes beginning the "march-in" process, a legal mechanism that allows the government to intervene when federally funded inventions are not being adequately commercialized or managed in accordance with federal law.