The Bay Area job market is facing significant disruptions as several companies announce layoffs and closures. Target is set to close its East Palo Alto location next month, impacting 85 employees. In the biotech sector, Bristol Myers will reduce its workforce in New Jersey by 117 positions through a staggered wave of cuts. Additionally, Cepheid, a Sunnyvale-based biotech firm, has announced plans to lay off 635 employees, primarily in its manufacturing division. These developments reflect a broader trend of job reductions in the region, exacerbating concerns about employment stability.