The U.S. Supreme Court made several key decisions this week regarding arbitration exemptions and mandates. The Court rejected Vanda Pharmaceuticals Inc.'s request to review Federal Circuit decisions on patent invalidity and declined to review cases involving arbitration exemptions for delivery drivers from Amazon, Domino's Pizza, and a subsidiary of Flowers Foods. Additionally, the Court denied Amazon's bid to review a Ninth Circuit decision regarding last-mile delivery drivers' exemption from the Federal Arbitration Act. In a related development, Domino's drivers can now pursue their wage and hour class action after the Court declined to review their exemption from mandatory arbitration. Furthermore, Uber and Lyft have requested the Supreme Court to block state officials from bypassing arbitration mandates.