France has confirmed its first outbreak of lumpy skin disease (dermatose nodulaire contagieuse, DNC) in cattle, detected in a bovine farm in Savoie in late June 2025. This highly infectious viral disease affects cattle but is not transmissible to humans. Authorities have ordered the culling of infected animals to contain the spread. Since the initial detection, multiple new outbreaks have been suspected and confirmed in Savoie and neighboring Haute-Savoie, with a total of eight affected farms reported by mid-July. The disease has impacted approximately 2,156 livestock farmers, leading to suspension of cheese sales and causing daily economic losses exceeding one million euros. The French government, along with local representatives and farmers, is coordinating response efforts, including ongoing inspections and awaiting vaccine deliveries from the European Union. Preventive vaccination campaigns have also been initiated in the affected regions and in neighboring Switzerland to curb further spread. Some farmers have resisted preventive culling measures, prompting authorities to reaffirm the necessity of euthanasia to control the outbreak. The dairy sector in the region faces significant challenges due to the disease's impact.