Recent analyses and expert assessments highlight the potential humanitarian and public health consequences of funding cuts under the Trump administration. Cuts to the United States Agency for International Development (USAID) are projected to result in approximately 14 million avoidable deaths globally by 2030, including a significant number of children. USAID funding has historically prevented about 90 million deaths between 2001 and 2021. The reduction in U.S. foreign aid, which accounts for around 40% of global humanitarian assistance, risks destabilizing international aid programs and organizations. Additionally, domestic policy changes propose deep cuts to Medicaid, potentially stripping $1 trillion from state funding and leaving an estimated 11.8 million Americans without health coverage. States such as Louisiana, California, and Nevada are expected to be disproportionately affected. A newly published report in JAMA Health Forum estimates that Medicaid cuts could lead to over 1,000 additional deaths annually. Efforts to preserve key health programs like PEPFAR, which is largely implemented through USAID funding, have seen some success in the Senate, but concerns remain about the broader impact of these budget reductions on global and domestic health outcomes.