Scarlett Johansson has become the highest-grossing lead actor of all time at the global box office, surpassing fellow Marvel Cinematic Universe stars Samuel L. Jackson and Robert Downey Jr. This milestone was achieved following the successful opening of her latest film, "Jurassic World: Rebirth," which grossed approximately $318 million worldwide during its debut weekend. Johansson's cumulative box office earnings from 36 lead roles now stand at around $14.8 billion, according to data from The Numbers and other industry sources. This record is noted before inflation adjustment. Johansson's accomplishment marks a new benchmark in Hollywood, highlighting her status as the industry's most bankable lead actor globally.