The San Francisco 49ers secured a 22-19 victory over the Las Vegas Raiders in a preseason game on August 16, 2025. Quarterback Brock Purdy returned to the field and was praised for his performance, completing 5 of 7 passes for 66 yards on the opening drive that resulted in a field goal. Backup quarterback Mac Jones also played, completing 13 of 16 passes for 135 yards but threw an interception. During the game, the 49ers lost starting guard Dominick Puni and undrafted rookie running back Corey Kiner to injuries, with Puni expected to be sidelined for several weeks. Kiner was subsequently waived/injured and is likely to revert to the injured reserve list if unclaimed. The team also released defensive lineman Demone Harris and signed veteran guard Michael Dunn, who has NFL experience with the Cleveland Browns, and wide receiver Malik Knowles, who had been with the team earlier in the camp. The 49ers' running back group currently includes Christian McCaffrey, Isaac Guerendo, Jeffery Wilson Jr., Ke’Shawn Vaughn, and emergency fullback Kyle Juszczyk, with Jordan James injured. Key offensive players such as George Kittle and Fred Warner have been leading the team during training camp, while Robbie Chosen showed increased explosiveness in practice. The 49ers are preparing for their final preseason tuneup at Levi’s Stadium, where former players and coaches, including Trey Lance and Jim Harbaugh, will reunite. Mac Jones suffered a knee injury during the preseason win, prompting the team to sign a former backup quarterback to compete for the No. 3 spot.