U.S. stocks concluded a volatile, holiday-shortened week with mixed outcomes, significantly influenced by healthcare sector movements. The Dow Jones Industrial Average fell 527 points, or 1.33%, closing at 39,142.23, primarily due to a 22% plunge in UnitedHealth Group Inc. shares after disappointing earnings. Conversely, the S&P 500 rose slightly by 0.13% to 5,282.70, supported by a 14% surge in Eli Lilly & Co. following promising trial results for a weight-loss drug. The Nasdaq Composite experienced a minor decline of 0.13% to 16,286.45. The week's market performance was shaped by ongoing tariff concerns, with investors closely watching trade negotiations and economic indicators. Despite declines in UnitedHealth and Nvidia, the broader market was buoyed by gains in other key stocks. Geopolitical tensions and economic policy uncertainties heightened market volatility. President Donald Trump's remarks on trade talks with Japan and the European Union, coupled with his criticism of Federal Reserve Chairman Jerome Powell, contributed to investor unease. The week closed with caution among investors regarding the potential global economic impact of tariffs.