Israeli military operations in the Gaza Strip have resulted in extensive casualties and destruction across multiple neighborhoods, including Gaza City, Khan Yunis, Jabalia, and the Al-Bureij refugee camp. Since early August 26, 2025, at least 51 Palestinians have been killed and numerous others injured due to airstrikes, drone attacks, artillery shelling, and ground assaults. Key affected areas include Al-Saftawi, Al-Sabra, Al-Karama, Al-Zaytoun, and Al-Mawasi. Several families have suffered heavy losses, such as the Abu Zubeida family in Al-Bureij, where multiple members were killed while asleep, and the Al-Dahshan family in Al-Sabra, with seven fatalities reported. Israeli drones have targeted civilian homes, including those sheltering displaced persons near schools and residential buildings, with some attacks involving explosive cubes dropped by quadcopter drones. Rescue operations have been hindered by ongoing strikes. Civilians, including women and children, have been directly targeted or caught in the crossfire during Israeli advances, particularly in the Al-Saftawi neighborhood, where seven Palestinians were killed and many wounded amid reports of Israeli forces firing on fleeing civilians. The Israeli military has also intensified its assault on the Sabra neighborhood, with residents resisting evacuation orders. The sustained bombardment has caused massive destruction to homes and infrastructure, with several buildings set ablaze or reduced to rubble. Medical sources and civil defense teams continue to report on the growing toll and challenges in reaching victims amid the ongoing conflict.