Congressional Republicans have approved President Donald Trump’s sweeping reconciliation package, dubbed the “One Big Beautiful Bill,” setting in motion what analysts at STAT describe as the largest reduction in federal health-care spending in U.S. history. The legislation pares more than $1 trillion from Medicaid and related programs over the next decade, according to documents reviewed by STAT, and redirects the savings to help finance a broad tax-cut slate favored by GOP leaders. Democratic lawmakers warn the measure could strip health coverage from roughly 17 million people and place additional strain on hospitals already facing workforce shortages. Sen. Jacky Rosen said Nevada’s limited pool of doctors and nurses will be stretched further, while Rep. Debbie Wasserman Schultz and Rep. Angie Craig predicted longer emergency-room waits and higher premiums for middle-class families. The bill drew an unusually muted response from the health-care industry, which failed to blunt the cuts despite intensive lobbying. Policy advisers and lobbyists told STAT the episode signals a sharp decline in the sector’s clout on Capitol Hill, even as Republicans brace for voter backlash in competitive districts. Vulnerable GOP lawmakers are now confronting questions about the scale of the Medicaid reductions as the party prepares to defend its House majority next year.