The United States Department of Agriculture (USDA) continues to report widespread detections of highly pathogenic avian influenza (HPAI) H5N1 across multiple species and states as of mid-2025. The total number of domestic cats infected with H5N1 has reached 141, with the latest case identified in New Jersey. Other mammals testing positive include rabbits in Maricopa, Arizona; red foxes in Costilla, Colorado; raccoons in Texas and New York; a skunk in Nevada; and a sheep in Great Britain. Numerous wild bird detections have been reported in various states including Arizona, New York, Pennsylvania, Michigan, California, Minnesota, Missouri, and others, involving species such as hawks, owls, eagles, vultures, geese, and pigeons. Notably, bird flu has caused at least 18 eagle deaths in Michigan this year. The USDA has also confirmed H5N1 infections in commercial poultry premises in North Yorkshire and Wales in the UK, and in a commercial game bird facility in Pennsylvania affecting 29,300 birds. The USDA extended the H5N1 dairy cow testing program until September 30, 2025, with five infected dairy herds now reported in Arizona. Agriculture Secretary Rollins provided updates on the bird flu strategy in late June 2025. The circulating virus strain in the US is identified as Eurasian lineage goose/Guangdong clade 2.3.4.4b genotype B3.13. These reports underscore the ongoing presence and geographic spread of H5N1 in wild and domestic animals across the US and parts of the UK.