Teresa Guadalupe Reyes Sahagún has resigned as head of Mexico's Comisión Nacional de Búsqueda (CNB), with her tenure concluding on August 31, 2025, according to the Secretaría de Gobernación (Segob). Reyes led the CNB for one year and ten months amid a national crisis of disappearances. Her resignation follows demands from various families' collectives and non-governmental organizations that criticized her lack of experience in investigating and searching for missing persons. The government has announced a public consultation process to select her successor, emphasizing transparency and openness. Mexico City Mayor Claudia Sheinbaum acknowledged Reyes's resignation, highlighting her sensitivity, conviction, and honesty, and confirmed Reyes will continue working in other government areas. This marks the second resignation at the CNB leadership within two years.